![]() ![]() A practical difficulty is that PWID commonly experience venous degradation as a complication of prolonged injection, making it a major barrier to obtaining blood samples by venipuncture. Another barrier to testing is the stigma and lack of trust exhibited by people who inject drugs (PWID) due to prior experiences in the healthcare system. ![]() This may often require multiple visits where reflex testing is not available, and thus a single visit is now advocated to reduce loss to follow-up. The current testing paradigm requires both detection of HCV antibodies to first diagnose any previous exposure, with subsequent HCV RNA testing to confirm active infection. The World Health Organization’s (WHO) goal of eliminating HCV as a public health threat by 2030 will require the availability of affordable, simple point-of-care tests. Accurate and reliable diagnosis of HCV infection is crucial for treatment and prevention. ![]() Hepatitis C virus (HCV) is a significant public health problem worldwide, affecting over 50 million people, and is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma. ![]()
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